Suppressive ketone

The boron-mediated ketone-ketone aldol reaction

The first examples of the directed, boron-mediated aldol reaction between different ketones are presented. Transformation of a variety of ketones to their corresponding boron enolates with Chx2BCl/Et3N, followed by reaction with acceptor ketones in diethyl ether, and oxidation of the resultant boron aldolate (H2O2, MeOH/pH 7 buffer), provided the aldol addition products. The reaction was most f...

Methyl ethyl ketone and methyl isobutyl ketone not carcinogenic.

Methyl Ethyl Ketone and Methyl Isobutyl Ketone Not Carcinogenic The April 22, 1993, issue of Environmental Health Perspectives contained a commentary by Legator and Strawn entitled "Public Health Policies Regarding Hazardous Waste Sites and Cigarette Smoking: An Argument by Analogy." Although the article does not include any discussion of either methyl ethyl ketone (MEK) or methyl isobutyl keto...

Ketone aldehydes in tissues.

Methyl ethyl ketone peroxide

Suppressive CpG

Cellular constipation can be deadly, according to a study on page 1587. Wang and colleagues show that cells get clogged with aborted secretory cargo when they lack an enzyme that helps form vesicles. Deletion of this enzyme proved lethal in mice, halting brain, bone and vascular development. The enzyme in question is a protein tyrosine phosphatase (PTP) called MEG2. MEG2 binds lipids and reside...